A patient in Korea has received the world’s first 3D printed windpipe transplant, marking a significant development in organ transplantation.
The female patient, in her 50s, underwent the procedure at Seoul St Mary’s Hospital following the loss of part of her windpipe due to thyroid cancer surgery.The transplant utilized a combination of stem cells, cartilage, and bio-ink to create a custom-fit organ.
Stem cells and cartilage cells obtained from other patients were incorporated into the 3D printed windpipe, along with polycaprolactone (PCL) for structural support. Notably, the patient did not require immunosuppressants post-transplant. The procedure, which involved designing the windpipe based on the patient’s CT and MRI data, took less than two weeks to print and was transplanted in a half-day surgery.
This achievement is the result of a collaborative effort between the Catholic University of Korea, Gachon University, and biomedical engineering company T&R Biofab. While the PCL component has a limited lifespan of five years, researchers are optimistic that during this period, the artificial organ will stimulate the regeneration of the patient’s trachea.
This technology offers hope for patients with thyroid cancer, congenital anomalies, or windpipe trauma, providing a safer and more effective treatment option compared to existing methods. The success of this pioneering procedure opens new possibilities in organ transplantation, demonstrating the potential of 3D printing technology to address the shortage of donor organs.
Although challenges remain, such as expanding production capabilities and regulatory approvals, the advancement represents a huge step towards changing medical treatment paradigms.
Source: sciencefocus.com
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